Lung Volume Reduction Coil Treatment vs Usual Care in Patients With Severe Emphysema The REVOLENS Randomized Clinical Trial -

Lung Volume Reduction Coil Treatment vs Usual Care in Patients With Severe Emphysema The REVOLENS Randomized Clinical Trial
Information type: Randomised controlled trials
Source: Journal of the American Medical Association
Specialities: Respiratory disorders
Summary
In this preliminary study of 100 patients with severe emphysema followed up for 6 months, bronchoscopic treatment with nitinol coils compared with usual care (bronchodilators with or without inhaled corticosteroids and oxygen) showed improved exercise capacity defined by the 6-mi
UKMi comment
Shape-memory nitinol coils are nonblocking devices bronchoscopically delivered into subsegmental airways to induce regional parenchymal volume reduction, enhance lung recoil, and re-establish small airway tethering.

The absolute between-group difference in 6-minute walk distance was only modestly improved (21 m).
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