UK Medicines Information
Neoadjuvant and adjuvant trastuzumab in patients with HER2-positive locally advanced breast cancer (NOAH): follow-up of a randomised controlled superiority trial with a parallel HER2-negative cohort
Information type:
Randomised controlled trials
Source:
The Lancet Oncology
Specialities:
Cancers
Summary
Long-term follow up results from a primary analysis of the NOAH trial suggest sustained benefit in event-free survival from trastuzumab-containing neoadjuvant therapy followed by adjuvant trastuzumab in locally advanced or inflammatory breast cancer (median follow up 5.4 years).
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