This systematic review has several limitations. “First, it does not address new or emerging therapies for community-acquired pneumonia or changing antimicrobial resistance patterns over time. Secondly, many of the studies included in the review were conducted prior to 2000. Third, few of these studies were high-quality randomised controlled trials. Fourth, for initial antibiotic selection, only antibiotics recommended by the Infectious Diseases Society of America and the American Thoracic Society guidelines were evaluated which therefore limits the generalisability these findings.”