Comparative Benefits and Harms of Antidepressants, Psychological, Complementary, and Exercise Treatments for Major Depression: An Evidence Report for a Clinical Practice Guideline From the American College of Physicians -

Comparative Benefits and Harms of Antidepressants, Psychological, Complementary, and Exercise Treatments for Major Depression: An Evidence Report for a Clinical Practice Guideline From the American College of Physicians
Information type: Systematic reviews
Source: Annals of Internal Medicine
Specialities: Mental health and illness
Summary
A systematic review of 45 trials comparing the benefits/harms of 2nd-generation antidepressants and psychological, complementary and alternative medicine, and exercise concludes similar efficacy of CBT and antidepressants for initial treatment of major depressive disorder.
UKMi comment
This review forms the basis of the American College of Physicians guideline on non-pharmacological versus pharmacological treatment of adults with major depressive disorder.
Related links: Link to guideline