A related commentary discusses this research. It notes that an important limitation of this study, which complicates the ability to draw conclusions for clinical practice, is the short median treatment duration of 6 weeks, which is particularly important because most patients receive chronic treatment. However this study expands on previous knowledge of the harmful effects of antipsychotics by ranking the risk for each metabolic adverse effect for each antipsychotic. Future research should attempt to identify genetic characteristics associated with efficacy and adverse effects to facilitate personalised psychiatry.