Effect of Vitamin D Supplementation on Blood Pressure A Systematic Review and Meta-analysis Incorporating Individual Patient Data

This meta-analysis of RCTs and individual patient data which reported blood pressure (BP) outcomes for patients on vitamin D supplementation for a minimum of 4 weeks (for any indication) showed no effect on systolic or diastolic BP.

NICE has issued a public health guideline (November 2014) for the use of vitamin D supplementation in the “at risk groups” identified as the following:

• infants and children aged under 5
• pregnant and breastfeeding women, particularly teenagers and young women
• people over 65
• people who have low or no exposure to the sun, for example, those who cover their skin for cultural reasons, who are housebound or confined indoors for long periods
• people with darker skin, for example, people of African, African-Caribbean or South Asian family origin