Efficacy and Safety of Testosterone Treatment in Men: An Evidence Report for a Clinical Practice Guideline by the American College of Physicians -

Efficacy and Safety of Testosterone Treatment in Men: An Evidence Report for a Clinical Practice Guideline by the American College of Physicians
Information type: Systematic reviews
Source: Annals of Internal Medicine
Specialities: Endocrine system disorders | Renal and urologic disorders
Summary
Review of 38 RCTs concludes that whilst moderate quality evidence suggests testosterone improves sexual functioning and quality of life, it had little to no effect on physical functioning, depressive symptoms, energy and vitality, or cognition.
UKMi comment

No trials were powered to assess cardiovascular events or prostate cancer, and most trials excluded men at increased risk for these conditions.

This review forms the basis of a clinical practice guideline issued by the American College of Physicians.
Related links: Editorial Clinical guideline