Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care: systematic review and meta-analysis -

Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care: systematic review and meta-analysis
Information type: Systematic reviews
Source: British Medical Journal
Specialities: Infection and infectious diseases | Paediatric and neonatal medicine | Renal and urologic disorders
Summary
This meta-analysis shows prevalence of resistance to commonly prescribed antibiotics (AB) in primary care in children with UTIs caused by E coli is high, and could render some AB ineffective as 1st-line treatments, particularly in case of previous exposure to AB (within 6 months)
UKMi comment
In a related editorial, authors comment that these findings make the case for a change in guidelines for “first choice” antibiotics in this setting.
Related links: Editorial