The Role of Macrolide Antibiotics in Increasing Cardiovascular Risk -

The Role of Macrolide Antibiotics in Increasing Cardiovascular Risk
Information type: Systematic reviews
Source: Journal of the American College of Cardiology
Specialities: Cardiovascular system disorders | Infection and infectious diseases
Summary
From this meta-analysis of 33 studies (n=20,779,693) patients taking macrolides were at more risk of sudden cardiac death or ventricular tachyarrhythmia (RR=2.42; 95% CI = 1.61 to 3.63). No association was found between macrolides use and all cause death or cardiovascular events
UKMi comment
The RRs associated with sudden cardiac death and ventricular tachyarrhythmia were 3.40 for azithromycin, 2.16 for clarithromycin, and 3.61 for erythromycin, respectively.
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