According to a commentary, widespread fascination with vitamin D as a panacea for most illnesses, including CVD is responsible for nearly a 100-fold increase in vitamin D testing and oral supplementation over the last decade, largely in populations at low risk for vitamin D deficiency. It suggests that the popularity of vitamin D supplementation is at least partly due to the misinterpretation of impressive epidemiologic associations between vitamin D status and a breadth of health metrics, leading to a potentially flawed assumption of causality.