Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants

Review (12 RCTs, n=5,425) showed that lactoferrin supplementation to enteral feeds decreased suspected or confirmed late‐onset sepsis but not necrotizing enterocolitis ≥ stage II, all-cause mortality or neurodevelopmental outcomes at 24 months of age in preterm infants.


Cochrane Database of Systematic Reviews