Evaluation of Time to Benefit of Statins for the Primary Prevention of Cardiovascular Events in Adults Aged 50 to 75 Years - A Meta-analysis

Review (8 RCTs; n=65,383 adults [66.3% men]) reports use of statins may reduce cardiac events for some of these adults with a life expectancy of at least 2.5 years (treating 100 for 2.5 years prevented 1 major adverse CV event in 1 adult); no data suggest a mortality benefit.

JAMA Internal Medicine