Family History of Gastric Cancer and Helicobacter pylori Treatment

RCT of first-degree relatives of patients with gastric cancer (GC, n=1676 modified intention-to-treat), H. pylori eradication treatment reduced risk of GC (over median follow-up 9.2 years, GC developed in 10 [1.2%] vs. 23 [2.7%] placebo; HR 0.45; 95% CI, 0.21-0.94; p=0.03).

New England Journal of Medicine