Fatal adverse drug reactions: a worldwide perspective in the WHO pharmacovigilance database

Fatal ADRs registered in VigiBase®, the WHO pharmacovigilance database (23 millions ADRs) during last 10 years correspond to just over 1% of total ADR numbers. They were reported mainly in patients >75 years and most frequently involved antineoplastics/immunomodulators.

British Journal of Clinical Pharmacology