Gilead reports positive results from two trials of remdesivir for COVID-19
In open-label, Phase III SIMPLE trial of 5-day and 10-day dosing of the drug in hospitalised patients with severe disease, patients on 10-day regimen had similar improvement in clinical status compared to patients on 5-day course. Positive data were also reported from NIAID trial
Source:
Biospace Inc.
SPS commentary:
In the SIMPLE trial:
Preliminary results from the National Institute of Allergy and Infectious Diseases (NIAID) sponsored Adaptive COVID-19 Treatment Trial (n=1063) showed those hospitalised with advanced COVID-19 and lung involvement on remdesivir recovered faster than patients on placebo (11 vs. 15 days), recovery defined as being well enough for hospital discharge/returning to normal activity level.