Gonadotrophin releasing hormone analogues for children and adolescents with gender dysphoria

Data from studies reporting impact on critical outcomes of gender dysphoria & mental health (depression, anger, anxiety), and important outcomes of body image & psychosocial impact are of very low certainty and suggest little change with GnRH analogues from baseline to follow-up.

SPS commentary:

This document will help inform the independent review into gender identity services for children and young people commissioned by NHS England and Improvement.

National Institute for Health and Care Excellence