Hookworm Treatment for Relapsing Multiple Sclerosis

RCT (n=66) reports no significant difference in new/enlarging/enhancing lesions for hookworm treatment vs placebo, however hookworm treatment increased T regulatory cells (4.4% for hookworm treatment vs 3.9% for placebo, p=0.001), suggesting an immunobiological effect of hookworm

Source:

JAMA Neurology