Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries

All 3 models used suggested high HPV vaccination coverage of girls can lead to cervical cancer elimination in the next 10 years; and screening with high uptake will expedite reductions and will be necessary to eliminate cervical cancer in countries with the highest burden.

SPS commentary:

In a separate analysis, mortality impact of achieving WHO cervical cancer elimination targets was studied in a related and comparative modelling analysis in 78 low-income and lower-middle-income countries. This analysis found that in the next 10 years, a one-third reduction in the rate of premature mortality from cervical cancer in low-income and lower-middle-income countries is possible. Author’s state successful implementation of the WHO elimination strategy would reduce cervical cancer mortality by almost 99% and save more than 62 million women's lives.


Authors of a related commentary state findings from these two modelling analyses show that considerable progress can be made in reducing the intolerable and preventable global burden of cervical cancer.


The Lancet

Resource links:

Comparative modelling analysis