Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries

All 3 models used suggested high HPV vaccination coverage of girls can lead to cervical cancer elimination in the next 10 years; and screening with high uptake will expedite reductions and will be necessary to eliminate cervical cancer in countries with the highest burden.

SPS commentary:

In a separate analysis, mortality impact of achieving WHO cervical cancer elimination targets was studied in a related and comparative modelling analysis in 78 low-income and lower-middle-income countries. This analysis found that in the next 10 years, a one-third reduction in the rate of premature mortality from cervical cancer in low-income and lower-middle-income countries is possible. Author’s state successful implementation of the WHO elimination strategy would reduce cervical cancer mortality by almost 99% and save more than 62 million women's lives.

 

Authors of a related commentary state findings from these two modelling analyses show that considerable progress can be made in reducing the intolerable and preventable global burden of cervical cancer.

Source:

The Lancet

Resource links:

Comparative modelling analysis

Commentary