In-Hospital Use of Statins Is Associated with a Reduced Risk of Mortality among Individuals with COVID-19

This retrospective analysis of data on 13,981 patients with COVID-19 in Hubei Province, China, found that use of statins was associated with a lower 28-day all-cause mortality rate (5.2% v 9.4% in matched patients not receiving statins; adjusted HR 0.58; 95% CI 0.43-0.80).

SPS commentary:

There has been speculation about whether statins could improve outcomes in Covid-19 patients as a result of their anti-inflammatory and immunomodulatory effects. The authors say their findings provide preliminary evidence for their use, and support the completion of ongoing prospective studies and randomised controlled trials involving statin treatment for Covid-19.

Cell Metabolism