Levetiracetam add‐on for drug‐resistant focal epilepsy

Update of previous review (14 RCTs; n=2455) found a 500 mg daily dose of levetiracetam is no more effective than placebo at reducing seizures; and odds of response (50% reduction in seizure frequency) are increased by nearly 40% for each 1000 mg increase in dose of levetiracetam.


Cochrane Database of Systematic Reviews