Long-term protection from HIV infection with oral HIV pre-exposure prophylaxis in gay and bisexual men: findings from the expanded and extended EPIC-NSW prospective implementation study

This pragmatic study in New South Wales (9596 high-risk participants dispensed pre-exposure prophylaxis; 98.3% gay or bisexual men) found HIV incidence remained low over up to 3 years of follow-up (HIV seroconversion incidence of 1.61 per 1000 person-years; 95% CI 1.13–2.30).

The Lancet HIV