Long-term safety and efficacy of emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV-1 pre-exposure prophylaxis: week 96 results from a randomised, double-blind, placebo-controlled, phase 3 trial

Ongoing RCT (n=5387) reports emtricitabine (EM) &(TN) tenofovir alafenamide is safe & effective for longer-term pre-exposure prophylaxis in cisgender men & transgender women who have sex with men, maintaining non-inferiority to EM & TN disoproxil fumarate; STD rates remained high

Source:

The Lancet HIV