Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure
RCT (n=2,928) found that among adult patients with acute hypoxemic respiratory failure in the ICU, a lower oxygenation target (PaO2 60 mm Hg) did not result in lower mortality than a higher target (PaO2 90 mm Hg) at 90 days (42.9% vs 42.4% mortality, RR 1.02, 95%CI 0.94-1.11).
Source:
New England Journal of Medicine