Medicines prescribed for asthma, discontinuation and perinatal outcomes, including breastfeeding: A population cohort analysis
Analysis of data on 107,573, 105,331, and 38,725 infants born 2000–2010 found that prescription of asthma medicines before or during pregnancy was linked to higher prevalence of adverse perinatal outcomes, particularly if prescriptions were discontinued during pregnancy.
Source:
PLOS ONE
SPS commentary:
Prescriptions for asthma, whether continued or discontinued during pregnancy, were associated with birth at<32 weeks’ gestation, small for gestational age <10th centile, (aOR 1.33 [1.10–1.61] and 1.10 [1.03–1.18], respectively). Discontinuation of asthma medicines in pregnancy was associated with birth at<37 weeks’ and <32 weeks’ gestation (aOR 1.22 [1.06–1.41] and 1.53 [1.11–2.10], respectively).