Mortality and critical care unit admission associated with the SARS-CoV-2 lineage B.1.1.7 in England: an observational cohort study

This observational cohort study (n=202,692) found patients with lineage B.1.1.7 were at increased risk of CCU admission & 28-day mortality vs patients with non-B.1.1.7 SARS-CoV-2. Mortality appeared independent of virus strain for critical care patients.

SPS commentary:

Study found a 65% higher risk of 28-day mortality associated with infection with lineage B.1.1.7 in patients tested in the community compared to patients infected with non-B.1.1.7 SARS-CoV-2. The risk of CCU admission for patients with lineage B.1.1.7 was double the risk associated with non-B.1.1.7 SARS-CoV-2 infection.

The Lancet Infectious Diseases