NICE amends recommendation on topiramate in guideline on diagnosis and management of headaches in over 12s (CG150)

NICE has amended recommendation 1.3.17 on topiramate for migraine prophylaxis to include discussion of the potential benefits and risks, and the importance of effective contraception for women and girls of childbearing potential when taking topiramate.

SPS commentary:

This is in line with updated safety advice on antiepileptics in pregnancy, which was issued by the MHRA in January 2021.

Source:

National Institute for Health and Care Excellence

Resource links:

MHRA advice