NIHR Signal: Tranexamic acid is safe to use following mild-to-moderate traumatic brain injury and reduces deaths

Expert commentary is provided for an RCT (n=12,737) which found fewer deaths from mild-moderate head injury in those given tranexamic acid vs placebo (5.8% vs 7.5%, RR 0.78, p<0.05), though the young age of the cohort raises concerns about applying the findings to older patients.

NIHR Dissemination Centre