Omega-3 and polyunsaturated fat for prevention of depression and anxiety symptoms: systematic review and meta-analysis of randomised trials

Review of 31 trials of long-chain omega-3 (n = 41,470), one of alpha-linolenic acid (n=4837), one of total polyunsaturated fat (n=4997) and none of omega-6, concludes long-chain omega-3 supplementation probably has little or no effect in preventing depression or anxiety symptoms.

British Journal of Psychiatry