Pharmacological interventions for treatment‐resistant depression in adults

Review (10 RCTs;n=2731) shows augmenting antidepressant therapy with mianserin or with antipsychotic (e.g.olanzapine, quetiapine) improves depressive symptoms (DSs) over short‐term but augmentation with mirtazapine does not produce clinically important benefit in reduction of DSs

Cochrane Database of Systematic Reviews