Pharmacotherapies for sleep disturbances in dementia

Review (9 RCTs, n=649) notably found no RCTs of many widely prescribed drugs (benzodiazepine, non‐benzodiazepine hypnotics, melatonin or melatonin receptor agonists). However, there was evidence of some beneficial effects on sleep outcomes from trazodone and orexin antagonists.

Source:

Cochrane Database of Systematic Reviews