Piperacillin/tazobactam-induced coagulopathy in a patient through a vitamin K-dependent mechanism
Case report describes 70-year-old female patient whose INR increased following piperacillin/tazobactam (PTZ). Coagulopathy was reversed with vitamin K, suggesting PTZ can induce coagulopathy through a vitamin K-dependent mechanism.
Source:
European Journal of Hospital Pharmacy