Prescribing medicines to older people—How to consider the impact of ageing on human organ and body functions
Review summarises most clinically relevant changes in human organ and body functions and consequential changes in pharmacokinetics and pharmacodynamics in older people, along with possible dosing consequences or alternatives for drugs frequently prescribed to this population
Source:
British Journal of Clinical Pharmacology
SPS commentary:
This article is part of a themed issue of the journal on medicines development to improve clinical outcomes in an increasingly older and multi‐morbid patient population, which notes that athough the longevity trend has been ongoing for decades, drug development and treatment have not really caught up.