Reappraisal of the treatment duration of antibiotic regimens for acute uncomplicated cystitis in adult women: a systematic review and network meta-analysis of 61 randomised clinical trials
Review of 61 RCTs (n=20,780) suggests shorter courses of third- and fourth-generation fluoroquinolones than that currently recommended are associated with similar effects; evidence for third generation cephalosporins and co-amoxiclav was of low quality.
Source:
The Lancet Infectious Diseases
SPS commentary:
A related comment notes that the authors are rightfully cautious in their conclusions, noting that the studies had methodological flaws and that further research is needed to confirm the findings.