Revised SPC: Atripla (tenofovir disoproxil fumarate/efavirenz/emtricitabine) tablets

SPC does not recommend co-administration of glecaprevir/pibrentasvir with Atripla and due to occasional reports of contraceptive failure with etonogestrel in efavirenz-exposed pts, a reliable method of barrier contraception must be used in addition to hormonal contraceptives.

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