Revised SPC: Epilim (sodium valproate) – all formulations and strengths
SPC updated with interaction with metamizole which may decrease sodium valproate levels with concomitant administration; prescribers advised to monitor clinical response and consider monitoring sodium valproate levels as appropriate.
Source:
electronic Medicines compendium
SPS commentary:
The SPC for valproate semisodium (Depakote) has also been updated to include this interaction.