Revised SPC: Epilim (sodium valproate) – all formulations and strengths

SPC updated with interaction with metamizole which may decrease sodium valproate levels with concomitant administration; prescribers advised to monitor clinical response and consider monitoring sodium valproate levels as appropriate.

SPS commentary:

The SPC for valproate semisodium (Depakote) has also been updated to include this interaction.

Source:

electronic Medicines compendium

Resource links:

SPC for valproate semisodium (Depakote)