Revised SPC: Kevzara (sarilumab) solution for injection in pre-filled pen- all strengths

SPCs updated to advise that most patients who developed GI perforations on sarilumab were taking concomitant NSAIDs, corticosteroids, or methotrexate, but their contribution relative to sarilumab in development of the adverse event is not known.

Source:

electronic Medicines compendium