Revised SPC: Mysimba 8 mg/90 mg (naltrexone hydrochloride/bupropion hydrochloride) prolonged-release tablets

SPC warns that co-administration of naltrexone/bupropion with digoxin may decrease plasma digoxin levels. Therefore monitor digoxin levels and signs of toxicity on stopping. Furthermore lupus erythematosus has been added as possible adverse reaction of unknown frequency.

Source:

electronic Medicines compendium