Revised SPC: Ovranette (ethinylestradiol/ levonorgestrel) tablets

SPC contraindicates concomitant use with ombitasvir/paritaprevir/ritonavir, dasabuvir, glecaprevir/pibrentasvir & sofosbuvir/velpatasvir/voxilaprevir owing to significant increases in ALT levels, and warns that oestrogens may induce or exacerbate hereditary & acquired angioedema.

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