Revised SPC: Picolax (sodium picosulfate; magnesium oxide; citric acid) powder for oral solution

SPC warns that the additional clear liquid to be taken with this product should not be only water. Drinking only water may lead to electrolyte imbalance, which in severe cases, may lead to complications such as seizures and coma.

SPS commentary:

Picolax has been reclassified from P to POM.

SPC also details and interaction with tetracycline/fluoroquinolone antibiotics, iron, digoxin, chlorpromazine and penicillamine which may chelate with the magnesium in this product.

Source:

electronic Medicines compendium