Revised SPC: Rocephin (ceftriaxone) Powder for Solution for Injection or Infusion

SPC updated to note encephalopathy has been reported with the use of ceftriaxone, particularly in elderly patients with severe renal impairment or CNS disorders. If it is suspected (e.g. decreased level of consciousness, altered mental state), discontinuation should be considered

Source:

electronic Medicines compendium