Revised SPC: Triumeq (lamivudine/abacavir sulfate/dolutegravir sodium) 50 mg/600 mg/300 mg film-coated tablets

In vitro study found concomitant administration of single dose riociguat (0.5 mg) and combination of abacavir/dolutegravir/lamivudine (600mg/50mg/300mg once daily) led to 3-fold higher riociguat levels. Elevated bilirubin levels added as a rare side-effect of treatment.

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