Revised SPC: Xagrid (anagrelide) 0.5mg hard capsule
SPC notes that CYP1A2 inducers (such as omeprazole) could decrease the exposure of anagrelide, therefore, clinical and biological monitoring is recommended in patients taking concomitant CYP1A2 inducers with anagrelide dose adjustment if necessary.
Source:
electronic Medicines compendium