Revised SPCs: Indivina (medroxyprogesterone acetate/estradiol valerate) tablets – all strengths

Large meta-analysis showed that after stopping treatment, excess risk of breast cancer will decrease with time and time needed to return to baseline depends on duration of prior HRT use; when taken for more than 5 years, the risk may persist for 10 years or more.

Source:

electronic Medicines compendium