Rifabutin-Based Triple Therapy (RHB-105) for Helicobacter pylori Eradication: A Double-Blind, Randomized, Controlled Trial

RCT (n=455) found a superior eradication rate with a combination of rifabutin, amoxicillin and omeprazole vs amoxicillin and omeprazole (83.8% vs 57.7%, p<0.001). Diarrhoea was more common with the rifabutin combination regimen (10.1% vs 7.9%).

Source:

Annals of Internal Medicine