Sodium bicarbonate to improve physical function in patients over 60 years with advanced chronic kidney disease: the BiCARB RCT

RCT (n=300) found oral sodium bicarbonate did not improve a range of health measures; there was no significant treatment effect for between-group difference in Short Physical Performance Battery score at 12 months (–0.4 points, 95% CI, –0.9 to 0.1 points; p = 0.15).


National Institute for Health Research