SPC Update: Zamadol (tramadol hydrochloride) 50 mg capsules
SPC updated to include MHRA warnings on the risk of dependence and addiction with opioids.
Source:
electronic Medicines compendium
Resource links:
Drug Safety Update - Opioids: risk of dependence and addiction
SPS commentary:
SPC update will support healthcare professionals to implement some of the recommendations from the MHRA alert from 2020 which outlines the risks of dependence and addiction associated with prolonged use of opioids for non-cancer pain.