The Exclusion of Older Persons From Vaccine and Treatment Trials for Coronavirus Disease 2019—Missing the Target

Results of review (847 RCTs) indicate older adults are likely to be excluded from more than 50% of COVID-19 trials and 100% of vaccine trials. Authors’ warn such exclusion will limit the ability to evaluate the efficacy, dosage, and adverse effects of the intended treatments.

JAMA Internal Medicine