Therapeutic blockade of granulocyte macrophage colony-stimulating factor (GM-CSF) in COVID-19-associated hyperinflammation: challenges and opportunities

Article covers the biochemistry of GM-CSF and suggests it may be a therapeutic target in COVID-19 hyperinflammation. It discusses potential risks of inhibition of GM-CSF in viral infection and the challenges of doing clinical trials in this setting.


The Lancet Respiratory Medicine