Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial
In RCT (n=210), primary skin fibrosis endpoint was not met, whilst findings for secondary endpoint of FVC% predicted indicate tocilizumab might preserve lung function in people with early systemic sclerosis-associated interstitial lung disease and elevated acute-phase reactants.
Source:
The Lancet Respiratory Medicine