Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne

Review of 49 trials (n=3880) found, compared to benzoyl peroxide, azelaic acid (AA) probably leads to a worse treatment response. When compared to tretinoin, AA probably makes little or no difference to treatment response. For other comparisons the quality of evidence was low.

Source:

Cochrane Database of Systematic Reviews