Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne

Review of 49 trials (n=3880) found, compared to benzoyl peroxide, azelaic acid (AA) probably leads to a worse treatment response. When compared to tretinoin, AA probably makes little or no difference to treatment response. For other comparisons the quality of evidence was low.


Cochrane Database of Systematic Reviews